What is vitamin E and what does it do?
Vitamin E is a fat-soluble nutrient found in many foods. In the body, it acts as an antioxidant, helping to protect cells from the damage caused by free radicals. Free radicals are compounds formed when our bodies convert the food we eat into energy. People are also exposed to free radicals in the environment from cigarette smoke, air pollution, and ultraviolet light from the sun.
The body also needs vitamin E to boost its immune system so that it can fight off invading bacteria and viruses. It helps to widen blood vessels and keep blood from clotting within them. In addition, cells use vitamin E to interact with each other and to carry out many important functions.
How much vitamin E do I need?
The amount of vitamin E you need each day depends on your age. Average daily recommended intakes are listed below in milligrams (mg) and in International Units (IU). Package labels list the amount of vitamin E in foods and dietary supplements in IU.
| Life Stage |
Recommended Amount |
|---|
| Birth to 6 months | 4 mg (6 IU) |
| Infants 7–12 months | 5 mg (7.5 IU) |
| Children 1–3 years | 6 mg (9 IU) |
| Children 4–8 years | 7 mg (10.4 IU) |
| Children 9–13 years | 11 mg (16.4 IU) |
| Teens 14–18 years | 15 mg (22.4 IU) |
| Adults | 15 mg (22.4 IU) |
| Pregnant teens and women | 15 mg (22.4 IU) |
| Breastfeeding teens and women | 19 mg (28.4 IU) |
What foods provide vitamin E?
Vitamin E is found naturally in foods and is added to some fortified foods. You can get recommended amounts of vitamin E by eating a variety of foods including the following:
- Vegetable oils like wheat germ, sunflower, and safflower oils are among the best sources of vitamin E. Corn and soybean oils also provide some vitamin E.
- Nuts (such as peanuts, hazelnuts, and, especially, almonds) and seeds (like sunflower seeds) are also among the best sources of vitamin E.
- Green vegetables, such as spinach and broccoli, provide some vitamin E.
- Food companies add vitamin E to some breakfast cereals, fruit juices, margarines and spreads, and other foods. To find out which ones have vitamin E, check the product labels.
What kinds of vitamin E dietary supplements are available?
Vitamin E supplements come in different amounts and forms. Two main things to consider when choosing a vitamin E supplement are:
- The amount of vitamin E: Most once-daily multivitamin-mineral supplements provide about 30 IU of vitamin E, whereas vitamin E-only supplements usually contain 100 to 1,000 IU per pill. The doses in vitamin E-only supplements are much higher than the recommended amounts. Some people take large doses because they believe or hope that doing so will keep them healthy or lower their risk of certain diseases.
- The form of vitamin E: Although vitamin E sounds like a single substance, it is actually the name of eight related compounds in food, including alpha-tocopherol. Each form has a different potency, or level of activity in the body.
Vitamin E from natural (food) sources is listed as "d-alpha-tocopherol" on food packaging and supplement labels. Synthetic (laboratory-made) vitamin E is listed as "dl-alpha-tocopherol." The natural form is more potent. For example, 100 IU of natural vitamin E is equal to about 150 IU of the synthetic form.
Some vitamin E supplements provide other forms of the vitamin, such as gamma-tocopherol, tocotrienols, and mixed tocopherols. Scientists do not know if any of these forms are superior to alpha-tocopherol in supplements.
Am I getting enough vitamin E?
The diets of most Americans provide less than the recommended amounts of vitamin E. Nevertheless, healthy people rarely show any clear signs that they are not getting enough vitamin E (see next question for information on the signs of vitamin E deficiency).
What happens if I don't get enough vitamin E?
Vitamin E deficiency is very rare in healthy people. It is almost always linked to certain diseases where fat is not properly digested or absorbed. Examples include Crohn's disease, cystic fibrosis, and certain rare genetic diseases such as abetalipoproteinemia and ataxia with vitamin E deficiency (AVED). Vitamin E needs some fat for the digestive system to absorb it.
Vitamin E deficiency can cause nerve and muscle damage that results in loss of feeling in the arms and legs, loss of body movement control, muscle weakness, and vision problems. Another sign of deficiency is a weakened immune system.
What are some effects of vitamin E on health?
Scientists are studying vitamin E to understand how it affects health. Here are several examples of what this research has shown.
Heart disease
Some studies link higher intakes of vitamin E from supplements to lower chances of developing heart disease. But the best research finds no benefit. People in these studies are randomly assigned to take vitamin E or a placebo (dummy pill with no vitamin E or active ingredients) and they don't know which they are taking. Vitamin E supplements do not seem to prevent heart disease, reduce its severity, or affect the risk of death from this disease. Scientists do not know whether high intakes of vitamin E might protect the heart in younger, healthier people who do not have a high risk of heart disease.
Cancer
Most research indicates that vitamin E does not help prevent cancer and may be harmful in some cases. Large doses of vitamin E have not consistently reduced the risk of colon and breast cancer in studies, for example. A large study found that taking vitamin E supplements (400 IU/day) for several years increased the risk of developing prostate cancer in men. Two studies that followed middle-aged men and women for 7 or more years found that extra vitamin E (300–400 IU/day, on average) did not protect them from any form of cancer. However, one study found a link between the use of vitamin E supplements for 10 years or more and a lower risk of death from bladder cancer.
Vitamin E dietary supplements and other antioxidants might interact with chemotherapy and radiation therapy. People undergoing these treatments should talk with their doctor or oncologist before taking vitamin E or other antioxidant supplements, especially in high doses.
Eye disorders
Age-related macular degeneration (AMD), or the loss of central vision in older people, and cataracts are among the most common causes of vision loss in older people. The results of research on whether vitamin E can help prevent these conditions are inconsistent. Among people with early-stage AMD, a supplement containing large doses of vitamin E combined with other antioxidants, zinc, and copper showed promise for slowing down the rate of vision loss.
Mental function
Several studies have investigated whether vitamin E supplements might help older adults remain mentally alert and active as well as prevent or slow the decline of mental function and Alzheimer's disease. So far, the research provides little evidence that taking vitamin E supplements can help healthy people or people with mild mental functioning problems to maintain brain health.
Can vitamin E be harmful?
Eating vitamin E in foods is not risky or harmful. In supplement form, high doses of vitamin E might increase the risk of bleeding (by reducing the blood's ability to form clots after a cut or injury) and of serious bleeding in the brain (known as hemorrhagic stroke). The highest safe level of intake from supplements for adults is 1,500 IU/day for natural forms of vitamin E and 1,100 IU/day for the synthetic form. The highest safe levels for children are lower than for adults. Some recent research suggests that intakes of vitamin E below these upper safe levels could increase the risk of prostate cancer in men. Vitamin E might also increase the risk of death in some adults with chronic health conditions, but this does not seem to be the case in healthy people.
Are there any interactions with vitamin E that I should know about?
Vitamin E dietary supplements can interact or interfere with certain medicines that you take. Here are some examples:
- Vitamin E can increase the risk of bleeding in people taking anticoagulant or antiplatelet medicines, such as warfarin (Coumadin®).
- In one study, vitamin E plus other antioxidants (such as vitamin C, selenium, and beta-carotene) reduced the heart-protective effects of two drugs taken in combination (a statin and niacin) to affect blood-cholesterol levels.
- Taking antioxidant supplements while undergoing chemotherapy or radiation therapy for cancer could alter the effectiveness of these treatments.
Tell your doctor, pharmacist, and other health care providers about any dietary supplements and medicines you take. They can tell you if those dietary supplements might interact or interfere with your prescription or over-the-counter medicines, or if the medicines might interfere with how your body absorbs, uses, or breaks down nutrients.
Where can I find out more about vitamin E?
- For general information on vitamin E:
- For more information on food sources of vitamin E:
- For more advice on buying dietary supplements:
- For information on the government's food guidance system:
Disclaimer
This fact sheet by the Office of Dietary Supplements provides information that should not take the place of medical advice. We encourage you to talk to your health care providers (doctor, registered dietitian, pharmacist, etc.) about your interest in, questions about, or use of dietary supplements and what may be best for your overall health. Any mention in this publication of a specific brand name is not an endorsement of the product.
Glossary
- age-related macular degeneration
- AMD. An eye disease that results in a loss of central, "straight-ahead" vision. AMD is the leading cause of vision loss in older Americans.
- alpha-tocopherol
- The form of vitamin E that is found in the largest amount in humans and is the most active form of vitamin E. It is an antioxidant.
- antioxidant
- A substance that protects cells from damage caused by free radicals (compounds formed during the metabolism of oxygen). It may help prevent the development of some chronic diseases such as cancer. Antioxidants include beta-carotene; lutein; lycopene; vitamins A, C, and E; selenium; and zinc.
- bacteria
- Single-celled organisms that are too small to be seen without a microscope. Bacteria are found everywhere and may be helpful or harmful.
- beta-carotene
- A carotenoid found in carrots, cantaloupe, apricots, sweet potatoes, pumpkin, winter squash, mangos, collard greens, spinach, kale, broccoli, and other orange, red, and dark green fruits and vegetables.
- bladder cancer
- Uncontrolled growth of abnormal cells in the bladder (the organ that stores urine).
- cancer
- A group of diseases in which cells divide abnormally and without control, and spread to nearby tissues and other parts of the body. Without treatment, cancer can stop organs from working normally, damage body systems, and cause the patient to die. Cancer may be caused by multiple factors, such as radiation, sunlight, tobacco, certain viruses, and poisonous chemicals; however, the cause of many cancers is unknown.
- cataract
- A condition in which the lens of the eye becomes cloudy. Symptoms include blurred, cloudy, or double vision; sensitivity to light; and difficulty seeing at night. Without treatment, cataracts can cause blindness. Cataracts occur in people of all ages but are most common in the elderly.
- cholesterol
- A substance found throughout the body. It is made by the liver and is an important component of cells. Cholesterol is also used to make hormones, bile acid, and vitamin D. Foods that come from animals contain cholesterol, including eggs, dairy products, meat, poultry and fish. High blood levels of cholesterol increase a person's chance (risk) of developing atherosclerosis and heart disease.
- fat soluble
- Able to be dissolved in fat.
- free radical
- An atom or molecule made in the body that can damage cells. A free radical has at least one unpaired electron, which makes it unstable. To become stable, the free radical takes an electron away from another atom, which makes that atom unstable, and starts a chain reaction that can injure cells. Free radicals are made during chemical changes that take place in a cell or an organism to produce energy and basic materials needed for important life processes (metabolism). They also come from tobacco smoke, pollution, radiation from the sun and x-rays, and other sources outside the body. Free radicals damage cells, cause genetic alterations (mutations), and may play a role in cancer, heart disease, and age-related diseases (such as Alzheimer’s, Parkinson’s, and Lou Gehrig’s diseases). Free radicals are also beneficial; they are involved in killing germs (microorganisms) and they help hormones and chemical messengers communicate with cells. Proteins (enzymes) made by the body, and vitamin C, vitamin E, and beta carotene in the diet help prevent free radical damage.
- immune system
- A group of organs and cells that defends the body against infection, disease, and altered (mutated) cells. It includes the thymus, spleen, lymphatic system (lymph nodes and lymph vessels), bone marrow, tonsils, and white blood cells.
- multivitamin/mineral dietary supplement
- MVM. A product that is meant to supplement the diet. MVMs contain a variety of vitamins and minerals. The number and amounts of these nutrients can vary substantially by product.
- nutrient
- A chemical compound in food that is used by the body to function and maintain health. Examples of nutrients include proteins, fats, carbohydrates, vitamins, and minerals.
- placebo
- An inactive substance or treatment that has no effect on the body and that ideally looks, smells, and tastes the same as, and is given the same way as, the active drug or treatment being tested. The effects of the active substance or treatment are compared to the effects of the placebo.
- prostate cancer
- Uncontrolled growth of abnormal cells in the prostate (a gland in the male reproductive system found below the bladder and in front of the rectum). Prostate cancer usually occurs in older men.
- selenium
- A mineral required in very small amounts to make important enzymes that are essential for good health. Selenium is found in some foods, including plant foods grown in selenium-rich soil, and some meats and seafood.
- stroke
- A loss of blood flow to part of the brain. Strokes are caused by blood clots or broken blood vessels in the brain, and result in damage to a section of brain tissue. Symptoms include dizziness, numbness, weakness on one side of the body, and problems with talking or understanding language. The chance (risk) of stroke is increased by high blood pressure, older age, smoking, diabetes, high cholesterol, heart disease, a family history of stroke, and a build-up of fatty material inside the coronary arteries (atherosclerosis). See also NIH publication: Know Stroke. Know the Signs. Act in Time. http://www.ninds.nih.gov/disorders/stroke/knowstroke.htm
- supplement
- A nutrient that may be added to the diet to increase the intake of that nutrient. Sometimes used to mean dietary supplement.
- virus
- An organism that can grow and multiply only inside the cells of living humans, plants, or animals. It is able to change (mutate) as it multiplies, which makes viral illnesses difficult to treat. Viruses cause many infections and diseases such as the common cold, AIDS (acquired immunodeficiency syndrome), herpes, and hepatitis.
- vitamin E
- A nutrient needed by the body to help keep the immune system healthy and to repair damage to DNA. It is an antioxidant that protects cells from free radical damage. Vitamin E is found in some foods, including vegetable oils, nuts and seeds, fortified breakfast cereals, and spinach, broccoli, kiwi, and mangos.