Dietary Supplements for Weight Loss

Fact Sheet for Consumers

What are weight-loss dietary supplements and what do they do?

The proven ways to lose weight are eating healthful foods, cutting calories, and being physically active. However, making these lifestyle changes isn’t easy, so you might wonder if taking a dietary supplement that’s promoted for weight loss might help.

This fact sheet describes what’s known about the safety and effectiveness of many ingredients that are commonly used in weight-loss dietary supplements. Sellers of these supplements might claim that their products help you lose weight by blocking the absorption of fat or carbohydrates, curbing your appetite, or speeding up your metabolism. However, there’s little scientific evidence that weight-loss supplements work. Many are expensive, some can interact or interfere with medications, and a few might be harmful.

If you’re thinking about taking a dietary supplement to lose weight, talk with your health care provider. This is especially important if you have high blood pressure, diabetes, heart disease, liver disease, or other medical conditions.

What are the ingredients in weight-loss dietary supplements?

Weight-loss supplements contain many ingredients—like herbs, fiber, and minerals—in different amounts and in many combinations. Sold in forms such as capsules, tablets, liquids, and powders, some products have dozens of ingredients.

Common ingredients in weight-loss supplements are described below in alphabetical order. You’ll learn what’s known about whether each ingredient works and is safe. Figuring out whether these ingredients really help you lose weight safely is complicated, though. Most products contain more than one ingredient, and ingredients can work differently when they’re mixed together.

You might be surprised to learn that makers of weight-loss supplements rarely carry out studies in people to find out whether their product works and is safe. And when studies are done, they usually involve only small numbers of people who take the supplement for just a few weeks or months. To know whether a weight-loss supplement can help people lose weight safely and keep it off, larger groups of people need to be studied for a longer time.

Common ingredients in weight-loss dietary supplements

INGREDIENT	DOES IT WORK?	IS IT SAFE?
African mango
African mango African mango seed extract is claimed to curb the formation of fat tissue.	Does it work? African mango might help you lose a very small amount of weight.	Is it safe? African mango seems to be safe, but its safety hasn’t been well studied. It can cause headache, sleeping problems, flatulence, and gas.
Beta-glucans
Beta-glucans Beta-glucans are soluble dietary fibers in bacteria, yeasts, fungi, oats, and barley. They might slow down the time it takes for food to travel through your digestive system, making you feel fuller.	Does it work? Beta-glucans don't seem to have any effect on body weight.	Is it safe? Beta-glucans seem to be safe (at up to 10 grams [g] a day for 12 weeks). They can cause flatulence.
Bitter orange
Bitter orange Bitter orange contains synephrine (a stimulant). It’s claimed to burn calories, increase fat breakdown, and decrease appetite. Products with bitter orange usually also contain caffeine and other ingredients. Bitter orange is in some weight loss dietary supplements that used to contain ephedra, another stimulant-containing herb that was banned from the U.S. market in 2004 (see the section on Ephedra).	Does it work? Bitter orange might slightly increase the number of calories you burn. It might also reduce your appetite a little, but whether it can help you lose weight is unknown.	Is it safe? Bitter orange might not be safe. Supplements with bitter orange can cause chest pain, anxiety, headache, muscle and bone pain, a faster heart rate, and higher blood pressure.
Caffeine
Caffeine Caffeine is a stimulant that can make you more alert, give you a boost of energy, burn calories, and increase fat breakdown. Often added to weight-loss dietary supplements, caffeine is found naturally in tea, guarana, kola (cola) nut, yerba mate, and other herbs. The labels of supplements that contain caffeine don't always list it, so you might not know if a supplement has caffeine.	Does it work? Weight-loss dietary supplements with caffeine might help you lose a little weight or gain less weight over time. When you use caffeine regularly, however, you become tolerant of it. This tolerance might lessen any effect of caffeine on body weight over time.	Is it safe? Caffeine is safe for most adults at doses up to 400‒500 milligrams (mg) a day, but it can make you feel nervous, jittery, and shaky. It can also affect your sleep. At higher doses, it can cause nausea, vomiting, rapid heartbeat, and seizures. Combining caffeine with other stimulant ingredients can increase caffeine's effects.
Calcium
Calcium Calcium is a mineral you need for healthy bones, muscles, nerves, blood vessels, and many of your body's functions. It's claimed to burn fat and decrease fat absorption.	Does it work? Calcium—either from food or in weight-loss dietary supplements—probably doesn't help you lose weight or prevent weight gain.	Is it safe? Calcium is safe at the recommended amounts of 1,000 to 1,200 mg a day for adults. Too much calcium (more than 2,000–2,500 mg a day) can cause constipation and decrease your body's absorption of iron and zinc. Also, too much calcium from supplements (but not foods) might increase your risk of kidney stones.
Capsaicin
Capsaicin Capsaicin comes from chili peppers and makes them taste hot. It's claimed to help burn fat and calories and to help you feel full and eat less.	Does it work? Capsaicin hasn't been studied enough to know if it will help you lose weight.	Is it safe? Capsaicin is safe (at up to 33 mg a day for 4 weeks or 4 mg a day for 12 weeks), but it can cause stomach pain, burning sensations, nausea, and bloating.
Carnitine
Carnitine Your body makes carnitine, and it's also found in meat, fish, poultry, milk, and dairy products. In your cells, it helps break down fats.	Does it work? Carnitine supplements might help you lose a small amount of weight.	Is it safe? Carnitine supplements seem to be safe (at up to 2 g a day for 1 year or 4 g a day for 56 days). They can cause nausea, vomiting, diarrhea, abdominal cramps, and a fishy body odor.
Chitosan
Chitosan Chitosan comes from the shells of crabs, shrimp, and lobsters. It's claimed to bind fat in the digestive tract so that your body can't absorb it.	Does it work? Chitosan binds only a tiny amount of fat, not enough to help you lose much weight.	Is it safe? Chitosan seems to be safe (at up to 15 g a day for 6 months). However, it can cause flatulence, bloating, mild nausea, constipation, indigestion, and heartburn. If you're allergic to shellfish, you could have an allergic reaction to chitosan.
Chromium
Chromium Chromium is a mineral that you need to regulate your blood sugar levels. It's claimed to increase muscle mass and fat loss and decrease appetite and food intake.	Does it work? Chromium might help you lose a very small amount of weight and body fat.	Is it safe? Chromium in food and supplements is safe at recommended amounts, which range from 20 to 45 micrograms a day for adults. In larger amounts, chromium can cause watery stools, headache, weakness, nausea, vomiting, constipation, dizziness, and hives.
Coleus forskohlii
Coleus forskohlii Coleus forskohlii is a plant that grows in India, Thailand, and other subtropical areas. Forskolin, made from the plant's roots, is claimed to help you lose weight by decreasing your appetite and increasing the breakdown of fat in your body.	Does it work? Forskolin hasn't been studied much. So far, however, it doesn't seem to have any effect on body weight or appetite.	Is it safe? Forskolin seems to be safe (at 500 mg a day for 12 weeks), but it hasn't been well studied. It can cause frequent bowel movements and loose stools.
Conjugated linoleic acid
Conjugated linoleic acid Conjugated linoleic acid (CLA) is a fat found mainly in dairy products and beef. It's claimed to reduce your body fat.	Does it work? CLA may help you lose a very small amount of weight and body fat.	Is it safe? CLA seems to be safe (at up to 6 g a day for 1 year). It can cause an upset stomach, constipation, diarrhea, loose stools, and indigestion.
Fucoxanthin
Fucoxanthin Fucoxanthin comes from brown seaweed and other algae. It's claimed to help with weight loss by burning calories and decreasing fat.	Does it work? Fucoxanthin hasn't been studied enough to know if it will help you lose weight. Only one study in people included fucoxanthin (the other studies were in animals).	Is it safe? Fucoxanthin seems to be safe (at 2.4 mg a day for 16 weeks), but it hasn't been studied enough to know for sure.
Garcinia cambogia
Garcinia cambogia Garcinia cambogia is a tree that grows throughout Asia, Africa, and the Polynesian islands. Hydroxycitric acid in the fruit is claimed to decrease the number of new fat cells your body makes, suppress your appetite and thus reduce the amount of food you eat, and limit the amount of weight you gain.	Does it work? Garcinia cambogia has little to no effect on weight loss.	Is it safe? Garcinia cambogia seems to be fairly safe. However, it can cause headache, nausea, and symptoms in the upper respiratory tract, stomach, and intestines.
Glucomannan
Glucomannan Glucomannan is a soluble dietary fiber from the root of the konjac plant. It's claimed to absorb water in the gut to help you feel full.	Does it work? Glucomannan has little to no effect on weight loss. But it might help lower total cholesterol, LDL (bad) cholesterol, triglycerides, and blood sugar levels.	Is it safe? Most forms of glucomannan seem to be safe (at up to 15.1 g a day for several weeks in a powder or capsule form). It can cause loose stools, flatulence, diarrhea, constipation, and abdominal discomfort.
Green coffee bean extract
Green coffee bean extract Green coffee beans are unroasted coffee beans. Green coffee bean extract is claimed to decrease fat accumulation and help convert blood sugar into energy that your cells can use.	Does it work? Green coffee bean extract might help you lose a small amount of weight.	Is it safe? Green coffee bean extract seems to be safe (at up to 200 mg a day for 12 weeks). It might cause headache and urinary tract infections. Green coffee beans contain the stimulant caffeine, which can cause problems at high doses or when it's combined with other stimulants (see the section on Caffeine).
Green tea and green tea extract
Green tea and green tea extract Green tea (also called Camellia sinensis) is a common beverage all over the world. Green tea and green tea extract in some weight-loss supplements are claimed to reduce body weight by increasing the calories your body burns, breaking down fat cells, and decreasing fat absorption and the amount of new fat your body makes.	Does it work? Green tea might help you lose a small amount of weight.	Is it safe? Drinking green tea is safe, but taking green tea extract might not be. Green tea extract can cause constipation, abdominal discomfort, nausea, and increased blood pressure. In some people, it has been linked to liver damage.
Guar gum
Guar gum Guar gum is a soluble dietary fiber in some dietary supplements and food products. It's claimed to make you feel full, lower your appetite, and decrease the amount of food you eat.	Does it work? Guar gum probably doesn't help you lose weight.	Is it safe? Guar gum seems to be safe (at up to 30 g a day for 6 months) when it is taken with enough fluid. However, it can cause abdominal pain, flatulence, diarrhea, nausea, and cramps.
Guarana (see the section on Caffeine)
Hoodia
Hoodia Hoodia is a plant from southern Africa, where it's used as an appetite suppressant.	Does it work? There hasn't been much research on hoodia, but it probably won't help you eat less or lose weight. Analyses showed that some hoodia supplements sold in the past contained very little hoodia or none at all. It's not known whether this is true of hoodia supplements sold today.	Is it safe? Hoodia might not be safe. It can cause rapid heart rate, increased blood pressure, headache, dizziness, nausea, and vomiting.
Kola (or cola) nut (see the section on Caffeine)
Mate (see the section on Caffeine)
Probiotics
Probiotics Probiotics are microorganisms in foods, such as some yogurts, and some dietary supplements that help maintain or restore beneficial bacteria in your digestive tract.	Does it work? It’s unclear whether probiotic supplements have any effect on weight or body fat.	Is it safe? Probiotics are safe in healthy people but may cause gas or other gastrointestinal problems.
Pyruvate
Pyruvate Pyruvate is naturally present in your body. Pyruvate in weight-loss supplements is claimed to increase fat breakdown, reduce body weight and body fat, and improve exercise performance.	Does it work? Pyruvate in supplements might help you lose a small amount of weight.	Is it safe? Pyruvate seems to be safe (at up to 30 g a day for 6 weeks). It can cause diarrhea, gas, bloating, and rumbling noises in the intestines due to gas.
Raspberry ketone
Raspberry ketone Raspberry ketone, found in red raspberries, is claimed to be a fat burner.	Does it work? Raspberry ketone has only been studied as a weight-loss aid in combination with other ingredients and not alone. Its effects on body weight are unknown.	Is it safe? Raspberry ketone hasn't been studied enough to tell if it's safe.
Vitamin D
Vitamin D Your body needs vitamin D for good health and strong bones. People who are obese tend to have lower levels of vitamin D, but there is no known reason why taking vitamin D would help people lose weight.	Does it work? Vitamin D doesn't help you lose weight.	Is it safe? Vitamin D from foods and dietary supplements is safe at the recommended amounts of 15‒20 mcg (600‒800 International Units [IU]) a day for adults. Too much vitamin D (more than 100 mcg [4,000 IU] a day) can be toxic and cause nausea, vomiting, poor appetite, constipation, weakness, and irregular heartbeat.
White kidney bean/bean pod
White kidney bean/bean pod White kidney bean or bean pod (also called Phaseolus vulgaris) is a legume grown around the world. An extract of this bean is claimed to block the absorption of carbohydrates and suppress your appetite.	Does it work? Phaseolus vulgaris extract might help you lose a small amount of weight and body fat.	Is it safe? Phaseolus vulgaris seems to be safe (at up to 3,000 mg a day for 12 weeks). However, it might cause headaches, soft stools, flatulence, and constipation.
Yerba mate (see the section on Caffeine)
Yohimbe
Yohimbe Yohimbe is a West African tree. Yohimbe, which contains a compound called yohimbine, is an ingredient found in some dietary supplements claiming to increase weight loss, improve libido, increase muscle mass, or treat male sexual dysfunction.	Does it work? Yohimbe doesn't help you lose weight.	Is it safe? Yohimbe might not be safe (especially at yohimbine doses of 20 mg or higher). Use it only with guidance from your health care provider because the side effects can be severe. Yohimbe can cause headaches, high blood pressure, anxiety, agitation, rapid heartbeat, heart attack, heart failure, and death.

Ephedra, an ingredient banned from dietary supplements

Ephedra (also called má huáng) is a plant containing substances that can stimulate your nervous system, increase the amount of energy you burn, increase weight loss, and suppress your appetite. In the 1990s, ephedra was a popular ingredient in dietary supplements sold for weight loss and to enhance athletic performance. In 2004, the U.S. Food and Drug Administration (FDA) banned ephedra in dietary supplements, concluding that it isn’t safe. Ephedra can cause nausea, vomiting, anxiety, mood changes, high blood pressure, abnormal heartbeat, stroke, seizures, heart attack, and death.

How are weight-loss dietary supplements regulated?

FDA is the federal agency that oversees dietary supplements in the United States. Unlike over-the-counter and prescription drugs—which must be approved by FDA before they can be sold—dietary supplements don’t require review or approval by FDA before they are put on the market. Also, manufacturers don’t have to provide evidence to FDA that their products are safe or effective before selling these products.

When FDA finds an unsafe dietary supplement, it can remove the supplement from the market or ask the supplement maker to recall it. FDA and the Federal Trade Commission can also take enforcement action against companies that make false weight-loss claims about their supplements; add pharmaceutical drugs to their supplements; or claim that their supplements can diagnose, treat, cure, or prevent a disease.

For more information about dietary supplement regulations, see the Office of Dietary Supplements (ODS) publication, Dietary Supplements: What You Need to Know.

Can weight-loss dietary supplements be harmful?

Weight-loss supplements, like all dietary supplements, can have harmful side effects and might interact with prescription and over-the-counter medications. Many weight-loss supplements have ingredients that haven’t been tested in combination with one another, and their combined effects are unknown.

Tell your health care providers about any weight-loss supplements or other supplements you take. This information will help them work with you to prevent supplement-drug interactions, harmful side effects, and other risks.

Fraudulent and adulterated products

Be very cautious when you see weight-loss supplements with tempting claims, such as magic diet pill, melt away fat, and lose weight without diet or exercise. If the claim sounds too good to be true, it probably is. These products might not help you lose weight—and they could be dangerous.

Weight-loss products marketed as dietary supplements are sometimes adulterated with prescription drugs or controlled substances. These ingredients won’t be listed on the product label, and they could harm you. FDA puts out public notifications about tainted weight-loss products .

Interactions with medications

Like most dietary supplements, some weight-loss supplements can interact or interfere with other medicines or supplements you take. If you take dietary supplements and medications on a regular basis, be sure to talk about this with your health care provider.

Choosing a sensible approach to weight loss

Weight-loss supplements can be expensive, and they might not work. The best way to lose weight and keep it off is to follow a healthy eating pattern, reduce calories, and exercise regularly under the guidance of your health care provider.

As a bonus, lifestyle changes that help you lose weight might also improve your mood and energy level and lower your risk of heart disease, diabetes, and some types of cancer.

Where can I find out more?

For general information on weight-loss dietary supplements
- ODS Health Professional Fact Sheet on Weight-Loss Dietary Supplements
- Weighing the Claims in Diet Ads , Federal Trade Commission
For publications about weight control, obesity, physical activity, and nutrition
- The Weight-control Information Network, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH)
- Weight Control , MedlinePlus, NIH
For more advice on choosing dietary supplements
- ODS Frequently Asked Questions: Which brand(s) of dietary supplements should I purchase?
For information about building a healthy dietary pattern
- Dietary Guidelines for Americans
- MyPlate

Disclaimer

This fact sheet by the National Institutes of Health (NIH) Office of Dietary Supplements (ODS) provides information that should not take the place of medical advice. We encourage you to talk to your healthcare providers (doctor, registered dietitian, pharmacist, etc.) about your interest in, questions about, or use of dietary supplements and what may be best for your overall health. Any mention in this publication of a specific product or service, or recommendation from an organization or professional society, does not represent an endorsement by ODS of that product, service, or expert advice.

Glossary

absorption: In nutrition, the process of moving protein, carbohydrates, fats, and other nutrients from the digestive system into the bloodstream. Most absorption occurs in the small intestine.
adulterate: To make unsafe or impure by using contaminated or unneeded ingredients; using a strength or quality that is less than claimed; leaving out or substituting key ingredients; or using inferior manufacturing, processing, packaging, or storage procedures.
adverse event: An unwanted medical problem that occurs during treatment. Adverse events may be unrelated to the treatment or they may be caused by the therapy or procedure. For example, an adverse event may be caused by the toxic effects of a particular drug or dietary supplement or by an interaction with another therapy. Also called adverse effect and side effect.
cancer: A group of diseases in which cells divide abnormally and without control, and spread to nearby tissues and other parts of the body. Without treatment, cancer can stop organs from working normally, damage body systems, and cause the patient to die. Cancer may be caused by multiple factors, such as radiation, sunlight, tobacco, certain viruses, and poisonous chemicals; however, the cause of many cancers is unknown.
capsule: A gelatin shell containing a dose of medicine, a vitamin, or other dietary supplement.
control: In a clinical trial, the group of participants that does not receive the new treatment being studied. This group is compared with the group receiving the new treatment, to see whether the new treatment works. In an observational study, the controls are participants who do not have a particular health condition; the control group is compared with the group of participants who do have the condition to see if certain factors (such as diet, activity level, or use of dietary supplements) may be associated with developing or preventing the condition.
cure: To heal or restore health; a treatment to restore health.
diabetes: A disease in which blood sugar (glucose) levels are high because the body is unable to use glucose properly. Diabetes occurs when the body does not make enough insulin, which helps the cells use glucose, or when the body no longer responds to insulin.
diagnose: The process of using signs and symptoms to identify a disease.
dietary fiber: A substance in plants that you cannot digest. It adds bulk to your diet to make you feel full, helps prevent constipation, and may help lower the risk of heart disease and diabetes. Good sources of dietary fiber include whole grains (such as brown rice, oats, quinoa, bulgur, and popcorn), legumes (such as black beans, garbanzo beans, split peas, and lentils), nuts, seeds, fruit, and vegetables.
dietary supplement: A product that is intended to supplement the diet. A dietary supplement contains one or more dietary ingredients (including vitamins, minerals, herbs or other botanicals, amino acids, and other substances) or their components; is intended to be taken by mouth as a pill, capsule, tablet, or liquid; and is identified on the front label of the product as being a dietary supplement.
drug: Any substance (other than food) that is used to prevent, diagnose, treat, or relieve symptoms of a disease or abnormal condition. Also, a substance that alters mood or body function or that can be habit-forming or addictive, especially a narcotic.
effectiveness: In medicine, the ability of an intervention (for example, a drug, surgery, or a dietary supplement) to produce the desired beneficial effect under the usual conditions of care by a health care provider.
evidence: Information used to support the use of a particular screening procedure, treatment, or preventive measure. In medicine, evidence needed to determine effectiveness is provided by laboratory research, clinical trials, and other studies.
Federal Trade Commission: FTC. A federal agency that protects consumers by preventing deceptive and unfair business practices. This includes unfair or deceptive advertising and marketing practices.
Food and Drug Administration: FDA, Department of Health and Human Services. FDA is the Federal government agency responsible for ensuring that foods and dietary supplements are safe, wholesome and sanitary, and that drugs, medical devices, cosmetics, and food are honestly, accurately and informatively represented to the public. FDA regulates dietary supplements under a different set of regulations than those covering conventional foods and drug products (prescription and over-the-counter). The dietary supplement manufacturer is responsible for ensuring that a dietary supplement is safe before it is marketed. FDA is responsible for taking action against any unsafe dietary supplement product after it reaches the market. Generally, manufacturers do not need to get FDA approval before producing or selling dietary supplements.
heart attack: The blockage of an artery supplying blood and oxygen to the heart, resulting in the damage or death of a section of heart muscle.
herb: A plant used in cooking, in tea, and for medicinal purposes.
high blood pressure: A blood pressure measurement of 140/90 mmHg (millimeters of mercury) or higher is considered high blood pressure (hypertension). Blood pressure is the force of blood pushing against the walls of the arteries. Blood pressure measurements are written as two numbers, for example 120/80. The first number (the systolic pressure) measures the pressure when the heart beats and pumps out blood into the arteries. The second number (the diastolic pressure) measures the pressure when the heart is at rest between beats. High blood pressure is a condition that occurs when a person's blood pressure often measures above 140/90 or regularly stays at that level or higher. This condition usually has no symptoms but can be life-threatening. It damages the arteries and increases the chance of stroke, heart attack, kidney failure, and blindness. Also called hypertension.
ingredient: In a dietary supplement, an ingredient is a component of the product, such as the main nutrient (vitamin, mineral, herb, amino acid, or enzyme) or any binder, color, filler flavor, or sweetener. In herbal supplements, the common name and Latin name (the genus and species) of the plant is given in the ingredient list. On a dietary supplement label, the ingredients are listed by weight, with the ingredient used in the largest amount first on the list and the ingredient used in the least amount at the end of the list.
interaction: A change in the way a dietary supplement acts in the body when taken with certain other supplements, medicines, or foods, or when taken with certain medical conditions. Interactions may cause the dietary supplement to be more or less effective, or cause effects on the body that are not expected.
kidney disease: A condition that lessens the ability of the kidneys to filter wastes from the blood, keep blood chemical levels balanced, and make certain hormones. The two most common causes of kidney disease are diabetes and high blood pressure. People with long-term kidney disease may need dialysis or a kidney transplant to stay alive.
label: When referring to dietary supplements, information that appears on the product container, including a descriptive name of the product stating that it is a "supplement"; the name and place of business of the manufacturer, packer, or distributor; a complete list of ingredients; and each dietary ingredient contained in the product. Supplements must also include directions for use, nutrition labeling in the form of a Supplement Facts panel that identifies each dietary ingredient contained in the product and the serving size, amount, and active ingredients.
liver: A large organ located in the right upper abdomen. It stores nutrients that come from food, makes chemicals needed by the body, and breaks down some medicines and harmful substances so they can be removed from the body.
metabolism: All chemical changes that take place in a cell or an organism. These changes produce energy and basic materials needed for important life processes.
mineral: In nutrition, an inorganic substance found in the earth that is required to maintain health.
National Institutes of Health: NIH. The main organization in the federal government responsible for conducting and supporting medical research. It is composed of 27 Institutes and Centers that provide financial support to researchers in the United States and throughout the world to investigate ways to prevent, treat, and cure common and rare diseases. NIH is part of the US Department of Health and Human Services.
nausea: The uneasy feeling of having an urge to throw up (vomit).
nervous system: The brain and spinal cord, including the network of nerves that carry messages back and forth between the brain and all parts of the body. The nervous system controls what the body does.
nutrition: The process of eating, digesting, and absorbing nutrients (such as protein, carbohydrate, fat, vitamins, minerals, and water) from food to maintain the body, grow new cells, repair tissues, and supply energy. Nutrition is also the science of food, diet, and health.
obesity: A condition characterized by an excessive amount of body fat. Obesity can be assessed by calculating the body mass index (BMI). (BMI is a number that estimates the amount of body fat on a person, based on weight and height. In adults, a BMI of 30 or higher indicates obesity. Some people, such as bodybuilders or other athletes with a lot of muscle, can be overweight without having obesity. See: overweight.
Office of Dietary Supplements: ODS, Office of Disease Prevention, Office of Director, National Institutes of Health, Department of Health and Human Services. ODS strengthens knowledge and understanding of dietary supplements by evaluating scientific information, stimulating and supporting research, disseminating research results, and educating the public to foster an enhanced quality of life and health for the US population.
prescription: A written order from a health care provider for medicine, therapy, or tests.
prevent: To stop from happening.
risk: The chance or probability that a harmful event will occur. In health, for example, the chance that someone will develop a disease or condition.
seizure: Sudden changes in behavior caused by excessive electrical activity in the brain.
stroke: A loss of blood flow to part of the brain. Strokes are caused by blood clots or broken blood vessels in the brain, and result in damage to a section of brain tissue. Symptoms include dizziness, numbness, weakness on one side of the body, and problems with talking or understanding language. The chance (risk) of stroke is increased by high blood pressure, older age, smoking, diabetes, high cholesterol, heart disease, a family history of stroke, and a build-up of fatty material inside the coronary arteries (atherosclerosis). See also NIH publication: Know Stroke. Know the Signs. Act in Time. http://www.ninds.nih.gov/disorders/stroke/knowstroke.htm
supplement: A nutrient that may be added to the diet to increase the intake of that nutrient. Sometimes used to mean dietary supplement.
treat: To care for a patient with a disease by using medicine, surgery, or other approaches.

Updated: March 22, 2021 History of changes to this fact sheet