Assessing the Health Effects of Bioactive Food Components, San Diego, CA, April 1, 2005 banner image
This workshop reported on the lessons learned from the evidence-based reviews on omega-3 fatty acids conducted by the Agency for Healthcare Research and Quality (AHRQ) and examined how this knowledge can be applied to researching the health effects of other bioactive food components.
AGENDA
Friday, April 1, 2005
Chairs: Leila G. Saldanha, PhD, RD and Paul M. Coates, PhD, Office of Dietary Supplements (ODS), National Institutes of Health (NIH)
1:00 pmOpening Comments
Leila G. Saldanha, PhD, RD, Scientific Consultant, ODS, NIH
   Overview Bioactive Food Components Project (PDF, 131kB)
1:10 pmNIH Needs for Evaluating Dietary Supplement Efficacy and Safety: Omega-3 Fatty Acids.
Paul M. Coates, PhD, Director, ODS, NIH
   NIH Needs for Evidence Reviews (PDF, 88kB)
1:20 pmOverview of the Agency for Healthcare Research and Quality (AHRQ) Evidence-based Review Process
Kenneth S. Fink, MD, MGA, MPH, Director, Evidence-based Practice Centers Program, Agency for Healthcare Research and Quality
   AHRQ Evidence Review Process (PDF, 2404kB)
1:35 pmQuestions and Answers
1:45 pm Lessons Learned: Evaluating Effects of Omega-3 Fatty Acids on Cardiovascular Disease
Ethan Balk, MD MPH, Tufts-New England Medical Center, Boston, MA
   Omega-3 and CVD, Lessons Learned (PDF, 167kB)
Questions and Answers
2:30 pmBREAK
2:50 pmLessons Learned: Evaluating Effects of Omega-3 Fatty Acids on Asthma, Eye-health, Mental-health, and Maternal & Child Health
Howard Schachter, PhD, MA, University of Ottawa, Chalmers Research Group, Ontario, CANADA
   Omega-3 Lessons Learned From Evidence Reviews (PDF, 1122kB)
Questions and Answers
2:50 pmLessons Learned: Evaluating Effects of Omega-3 Fatty Acids on Immunological Disorders, Cancer, and Neurological Health
Sydne Newberry, PhD, Southern California/RAND Corporation, Santa Monica, CA
   Omega-3 and Immunological Disorders and Cancer, Lessons Learned (PDF, 954kB)
Questions and Answers
4:10 pmPanel Discussion
Translation of lessons learned to researching the health effects of other bioactive food components.
  1. How can systematic reviews help identify gaps in research design and reporting of research results? Further, what has been learned through the evidence-based reviews on omega-3 fatty acids that could improve the quality of studies?
  2. When generally accepted biomarkers or surrogate end-points for evaluating the effects of a bioactive food component on a disease or health related-condition are not available, how can researchers go about selecting these end-points for in their research - this includes animal and human research?
  3. Are current models (in-vitro, in-vivo, animal, human) for evaluating the effects of a bioactive food component on a disease or health related-condition adequate? How do these models contribute toward arriving at policy decisions?
5:00 pmADJOURN


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