Grant Abstract: Asian American Community Cohort of the New York Metropolitan Area

Grant Number: 3UH3HL169656-04S1
PI Name: Ahn
Project Title: Asian American Community Cohort of the New York Metropolitan Area

Abstract: itamin D and calcium supplements are widely used to maintain skeletal health and are commonly consumed together, yet detailed population-based data on supplement type, dose, frequency, formulation, and product characteristics remain limited for Chinese, Korean, and Indian American adults. This gap is particularly important because Asian Americans experience an elevated prevalence of low serum 25-hydroxyvitamin D and osteoporosis-related risk, while evidence on calcium and vitamin D supplementation in relation to cardiovascular health remains heterogeneous. This ODS Co-Funding Supplement will leverage the Multiethnic Observational Study in American Asian and Pacific Islander Communities at New York (MOSAAIC-NY) to develop and implement a multilingual and community-informed vitamin D and calcium supplement assessment protocol among 180 Chinese, Korean, and Indian American adults, with 60 participants from each group. We will characterize supplement use of vitamin D and calcium, generate standardized exposure variables, evaluate feasibility of enhanced supplement ascertainment, and develop a multilingual supplement use screener. This focused pilot will strengthen dietary supplement exposure assessment in a population with limited existing supplement data, report findings separately for each participant group, produce reusable and harmonized tools for adaptation across MOSAAIC sites, support future biomarker-informed and longitudinal supplement research in MOSAAIC-NY, and advance ODS priorities related to rigorous supplement-use evaluation, research capacity, and collaborative stewardship.

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