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Nutrient Metabolism in the Genetic Anemias and Dietary Supplements of Potential


NHLBI Workshop

Nutrient Metabolism in the Genetic Anemias and Dietary Supplements of Potential Benefit to Patients With Sickle Cell Disease 

May 24-25, 1999

Natcher Conference Center, NIH 


AGENDA
Monday, May 24, 1999
 
8:00 a.m. Welcome From Extramural
Dr. Carol Letendre
 
8:15 a.m. SESSION I: Nutrient Metabolism in the Genetic Anemias
Chair: Dr. Betram H. Lubin
8:15 a.m. Nutritional Considerations in Thalassemia
Dr. Patricia J. Giardina
8:45 a.m. Identifying Genetic Influences on Human Nutrition
Dr. Darrell L. Ellsworth
9:15 a.m. Nutrition and Hematopoiesis: An Overview
Dr. Punam Malik
 
9:45 a.m. Break
 
10:00 a.m. Energy and Protein Metabolism in Patients With Sickle Cell Disease
Dr. Paul J. Flakoll
10:30 a.m. Zinc and Trace Minerals
Dr. Ananda A. Prasad
11:00 a.m. Nutritional Implications of Iron Overload
Dr. James D. Cook
11:30 a.m. Red Cell Turnover: Characteristics of Normal and Pathological Red Cells as They Enter and Leave the Circulation
Dr. Marilyn J. Telen
12:00 p.m. Interaction of Antioxidant Nutrients and Implications for Genetic Anemia
Dr. Alvin C. Chan
12:30 p.m. Recommendations of the Panel to NHLBI
 
12:45 p.m. Lunch
 
1:45 p.m. SESSION II: Nutritional Status of Patients With Sickle Cell Disease
Chair: Dr. Griffin Rodgers
1:50 p.m. Introduction and Overview of the Problem
Dr. Doris L. Wethers
2:00 p.m. Nutritional Assessment in Sickle Cell Disease
Dr. Rupa Redding-Lallinger
2:30 p.m. Nutrition Issues in Patients With Sickle Cell Disease
Dr. Atul Singhal
3:00 p.m. Pediatric Studies in Sickle Cell Nutrition
Dr. Babette Zemel
3:30 p.m. General Discussion / Chair's Recommendations
4:15 p.m. Adjourn
6:00 p.m. Dinner Meeting
Guest Speaker: Dr. Charles Whitten
 
Tuesday, May 25, 1999
 
9:00 a.m. SESSION III: Minerals
Chair: Dr. Alan N. Schechter
9:00 a.m.  Erythrocyte Magnesium Deficiencies in Sickle Cell Disease and Beta Thalassemia: Role of Dietary Supplementation
Dr. Carlo Brugnara
9:30 a.m. Zinc in Sickle Cell Disease
Dr. Virginia Stallings
10:00 a.m. Discussant
Dr. Kwaku Ohene-Frempong
10:20 a.m. General Discussion/Chair's Recommendations
 
10:30 a.m. Break
 
10:45 a.m. SESSION IV: Antioxidants / Vitamins
Chair: Dr. Alvin C. Chan
10:50 a.m. Overview: Membane Therapy for Molecular Disease
Drs. S. Tsuyoshi Ohnishi and Gabriel B. Ogunmola
11:20 a.m. Homocysteine and Folate in Sickle Cell Disease
Dr. Sohail Rana
11:50 a.m. Arginine in Sickle Cell Disease
Dr. Elliott Vichinsky
 
12:20 p.m. Lunch
 
1:20 p.m. L-Glutamine Therapy for Sickle Cell Anemia
Dr. Yukata Niihara
1:50 p.m. Different Antioxidant Capacity of Specific Carotenoids in Endothelial Cell-Mediated LDL Oxidation
Dr. Earl H. Harrison
2:20 p.m. Dietary n-3 Fatty Acid Treatment Reduces the Frequency of Pain Episodes and the Prothrombotic State in Patients With Sickle Cell Disease
Dr. James R. Eckman
2:50 p.m. General Discussion / Chair's Recommendations
3:30 p.m. Adjourn