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Evidence-Based Review Program

Table of Contents

Description

In FY 2001, the NIH Office of Dietary Supplements (ODS) received a Congressional mandate to review the current scientific evidence on the efficacy and safety of dietary supplements and identify research needs. ODS responded by developing an evidence-based review program using the Evidence-based Practice Centers Program established by the Agency for Healthcare Research and Quality (AHRQ) to conduct systematic reviews of the scientific literature and prepare reports of their findings.

Nutrition Research Methodology Reports & Publications

Technical Reports

Methods Research Report & Associated Publication

Completed Evidence Reports

ODS, in collaboration with other NIH institutes and centers, has found these reports invaluable in presenting what is and is not known in a research area, thus laying a sound foundation for identifying gaps in knowledge and providing a strong scientific basis for the development of a research agenda.

ODS-sponsored evidence reports have resulted in the publication of a number of articles in the peer-reviewed literature, and have helped NIH make decisions on research priorities in these areas. The reports and associated publications are available through the links above by topic.

Full List of Evidence Reports & Publications

B Vitamins and Berries

Evidence Report

  • Balk E, Chung M, Raman G, Tatsioni A, Chew P, Ip S, DeVine D, Lau J. B Vitamins and Berries and Age-Related Neurodegenerative Disordersexternal link icon. Evidence Report/Technology Assessment No. 134. (Prepared by Tufts-New England Medical Center Evidence-based Practice Center under Contract No. 290-02-0022). AHRQ Publication No. 06-E008. Rockville, MD: Agency for Healthcare Research and Quality. April 2006.

Associated Publication

Ephedra

Evidence Report

Associated Publication

Related Information on Ephedra

Multivitamin/Mineral Supplements

Evidence Report

  • Huang HY, Cabellero B, Chang S, Alberg A, Semba R, Schneyer C, Wilson RF, Cheng TY, Prokopowicz G, Barnes GJ, Vassy J, Bass EB. Multivitamin/Mineral Supplements and Prevention of Chronic Diseaseexternal link icon. Evidence Report/Technology Assessment No. 139. (Prepared by The Johns Hopkins University Evidence-based Practice Center under Contract No. 290-02-0018). AHRQ Publication No. 06-E012. Rockville, MD: Agency for Healthcare Research and Quality. May 2006.

Associated Publications

Related Information on Multivitamins/Mineral Supplements

Omega-3 Fatty Acids

Related Information on Omega-3 Fatty Acids

Probiotics

Evidence Report

  • Hempel S, Newberry S, Ruelaz A, Wang Z, Miles JNV, Suttorp MJ, Johnsen B, Shanman R, Slusser W, Fu N, Smith A, Roth E, Polak J, Motala A, Perry T, Shekelle PG. Safety of Probiotics to Reduce Risk and Prevent or Treat Diseaseexternal link icon. Evidence Report/Technology Assessment No. 200. (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-2007-10062-I.) AHRQ Publication No. 11-E007. Rockville, MD: Agency for Healthcare Research and Quality. April 2011.

Associated Publication

Soy

Evidence Report

  • Balk E, Chung M, Chew P, Ip S, Raman G, Kupelnick B, Tatsioni A, Sun Y, Wolk B, DeVine D, Lau J. Effects of Soy on Health Outcomesexternal link icon. Evidence Report/Technology Assessment No. 126. (Prepared by Tufts-New England Medical Center Evidence-based Practice Center under Contract No. 290-02-0022.) AHRQ Publication No. 05-E024-2. Rockville, MD: Agency for Healthcare Research and Quality. August 2005.

Vitamin D

Evidence Reports

  • Cranney A, Horsely T, O'Donnell S, Weiler H, Puil L, Ooi D, Atkinson S, Ward L, Moher D, Hanley D, Fang M, Yazdi F, Garrity C, Sampson M, Barrowman N, Tsertsvadze A, Mamaladze V. Effectiveness and Safety of Vitamin D in Relation to Bone Healthexternal link icon. Evidence Report/Technology Assessment No. 158. (Prepared by Ottawa Evidence-based Practice Center under Contract No. 290-02-0021). AHRQ Publication No. 07-E013, Rockville, MD: Agency for Healthcare Research and Quality. August 2007.
  • Chung M, Balk EM, Brendel M, Ip S, Lau J, Lee J, Lichtenstein A, Patel K, Raman G, Tatsioni A, Terasawa T, Trikalinos TA. Vitamin D and Calcium: Systematic Review of Health Outcomesexternal link icon. Evidence Report/Technology Assessment No. 183. (Prepared by Tufts Evidence-based Practice Center under Contract No. 290-2007-10055-1). AHRQ Publication No. 09-E015, Rockville, MD: Agency for Healthcare Research and Quality. August 2009.

Associated Publications