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Dietary Supplement Analytical Methods and Reference Materials Program (AMRM)

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Analytical Methods for Dietary Supplements

woman scientist examining herb leavesAnalytical methods program area focuses on the development and validation of analytical methods that can be used to verify dietary ingredient and label content claims, as tools to meet dietary supplement current good manufacturing practice requirements, and to determine the amounts of constituents of dietary supplements. Current method development efforts favor methods for analytes with high potential public health significance.

Method development.

  • Focus is on the development of methods to identify and quantify adulterants, natural toxins, pesticides and toxic elements.

Method validation.  

  • Method validation activities are coordinated by AOAC International through a stakeholder panel funded through a contract by ODS.  Information about the AOAC Stakeholder Panel on Dietary Supplements and ways to participate are available on the AOAC website.external link icon
  • NIH Administrative supplements for support of single laboratory validation of quantitative analytical methods:  In an attempt to leverage basic biomedical research already supported by NIH and to capture and validate new methods when first developed, administrative supplements to certain active NIH awards may be obtained via PA 13-381external link icon to support validation of quantitative analytical methods developed as part of the parent award.