Dietary Supplement Analytical Methods and Reference Materials Program (AMRM)

The U.S. National Institutes of Health (NIH) Office of Dietary Supplements (ODS) has a mission to strengthen knowledge and understanding of dietary supplements. The thorough analytical characterization of dietary supplements is a critical step in demonstrating safety and understanding their health effects, and the ODS Analytical Methods and Reference Materials Program (AMRM) is focused on developing and disseminating resources that scientists and analysts need to ensure that the characterization of dietary supplements, natural products, and nutrient biomarkers are precise, accurate, and reliable.

Search for Reference Materials

The Reference Materials Search Tool (RMST) is a platform to identify reference materials relevant to chemical analysis of dietary supplements, foods, and other natural products, including materials made available with support from the AMRM Program.

Search for Select Analytical Methods and Reference Materials Publications

Combine keywords with AND, NOT and OR, or use "" to search a phrase. Enter a substance, plant, matrix, method, compound, etc. to query a curated list of publications on available reference materials, methods, and educational resources.

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AMRM Program Overview
AMRM Program Areas
Analytical Methods
Resources and activities to advance method development and rigorous validation

Reference Materials
Suites of matrix reference materials for making measurements of dietary ingredients and supplements, and clinical samples

Education and Outreach
Quality assurance programs, education and training, botanical identification resources, and more to improve analytical skills
Glossary of Terms

Courtesy: LC Sander & CA Rimmer, NIST