ODS Conferences and Workshops
Addressing Challenges in the Assessment of Botanical Dietary Supplement Safety
April 26–27, 2016
The safety of botanical dietary supplements is an important public health issue. This workshop engaged experts from multiple disciplines to focus on practical approaches for addressing challenges in botannicals such as developing methods and criteria for assessing phytoequivalence of botanicals, identifying active constituent(s) or patterns of biological response of botanicals, and assessing absorption, distribution, metabolism, and elimination of botanicals. Participants discussed the relative merits of dedicating scientific attention to identifying the active constituent(s) in botanicals and identifying biological signatures that are predictive of adverse events (biomarkers of effect). Presentations addressed promising approaches (e.g., high throughput screening, computational tools) and accompanying challenges for using these approaches to advance the understanding of the risks associated with botanical use. This workshop was co-sponsored by the National Institutes of Health (NIH) Office of Dietary Supplements and the National Institute of Environmental Health Sciences National Toxicology Program.
Options for Consideration of Chronic Disease Endpoints for Dietary Reference Intakes (DRIs)
March 10–11, 2015
This intensive workshop brought together experts to provide a forum to consider options for including chronic disease endpoints in the setting of future dietary reference intakes (DRIs). The DRIs are widely used in the design and evaluation of research studies and results, in planning and monitoring nutrition-related public health programs and initiatives, in assessing the nutritional status of individuals and groups, and in patient and consumer counseling and educational programs. The information will be used in planning for future DRI reviews. Panel experts included nutrition scientists, biostatisticians, epidemiologists, clinical trialists, and toxicologists.
Vitamin D Standardization Program (VDSP) Symposium: Tools to Improve Laboratory Measurement
November 14, 2013
The Office of Dietary Supplements (ODS), National Institutes of Health, established the Vitamin D Standardization Program (VDSP) in November 2010 to standardize the laboratory measurement of vitamin D status worldwide. Standardization is essential to improve the detection, evaluation, and treatment of vitamin D deficiency and insufficiency by making measurements of serum total 25-hydroxyvitamin D [25(OH)D] accurate and comparable over time, location, and laboratory procedure. ODS leads this collaborative effort with the National Institute of Standards and Technology (NIST); the Centers for Disease Control and Prevention (CDC); the Laboratory for Analytical Chemistry of Ghent University, Belgium; and the Vitamin D External Quality Assessment Scheme (DEQAS), U.K.; and the College of American Pathologists (CAP). Key VDSP participants also include the national health surveys from Australia, Canada, Germany, Ireland, Mexico, South Korea, the United Kingdom, and the United States; numerous consultants from around the world also participated. VDSP is part of the ODS Vitamin D Initiative.
The Use and Biology of Energy Drinks: Current Knowledge and Critical Gaps
August 15–16, 2013
"Energy" drinks are marketed as promoting alertness, concentration, energy, weight loss, athletic performance or stamina. Products within the scope of this workshop contain caffeine and other ingredients such as amino acids, vitamins, herbal supplements and sugar or other sweeteners. These drinks are the fastest growing component of the U.S. beverage market; half the consumers of these products are under 25. The published data on the biological effects of many of the ingredients in these products, and on their effects when combined, are limited.
Human Performance and Dietary Supplements Summit
August 9–10, 2012
Fitness professionals often find themselves on the front line answering questions about dietary supplements, including the latest research on use and safety. The Human Performance and Dietary Supplements Summit highlighted the science and helped fitness professionals translate it to meet the needs of pro athletes, the military, civilian public servants, and youth. Experts from the medical, nutrition, athletic performance, and military fields explored how to educate clients and tactical populations on the fundamentals, certification, and testing of dietary supplements. Continuing education credits were made available for certified personal trainers and registered dietitians. This Summit was co-sponsored by the National Institutes of Health (NIH) Office of Dietary Supplements, the National Strength and Conditioning Association, the American Society for Nutrition, and EAS Academy.
Probiotic Foods and Supplements: The Science and Regulations of Labeling
June 12, 2010
The goals of this symposium were to facilitate the exchange of ideas regarding labeling and substantiation of claims for probiotics among academic, industry and regulatory professionals and to discuss ways to translate and communicate research results in an understandable way to the consumer and to health professionals. The target audience included academicians interested in conducting research on health benefits of probiotics; scientists, communications experts and regulatory specialists from companies involved or interested in marketing probiotics; U.S. government regulatory experts tasked with oversight of probiotic foods and dietary supplement products; and other experts in the field interested in the development of probiotics for the U.S. market. This symposium was supported by the New York Academy of Sciences, the National Institutes of Health (NIH) Office of Dietary Supplements, the NIH National Center for Complementary and Alternative Medicine, and the U.S. Food and Drug Administration.
Economic Analysis of Nutrition Interventions: Methods, Research, and Policy
February 23–24, 2010
The workshop consisted of three half-day sessions that covered the methods, research, and policy of the economic analysis of nutrition interventions. Sessions featured focused podium presentations and panel discussions. Products of the workshop included a summary of the discussions, identification of knowledge gaps, and suggestions for future research initiatives.
Vitamin D Biomarkers Methods Workshop
December 16, 2009
The workshop consisted of a series of short, focused podium presentations interspersed with open discussion sessions on the currently available analytical methods and interpretation of findings. A final session summarized the discussions, identified knowledge gaps, and suggested a research agenda for future studies. The meeting was sponsored by ODS.
Soy Protein and Isoflavones Research: Challenges in Designing and Evaluating Intervention Studies
July 28–29, 2009
The purpose of this workshop was to provide guidance for the next generation of soy protein and isoflavone human research. Specifically, the workshop objectives were to: (1) identify methodological issues relative to exposures and interventions that may confound study results and interpretation, and (2) identify scientifically sound and useful options and solutions for dealing with these issues in the design, conduct, reporting of results, and interpretation of ongoing and future studies.
NIDA-ODS Symposium: Caffeine: Is the Next Problem Already Brewing?
July 7–8, 2009
7th International Conference on Diet and Activity Methods
June 5–7, 2009
Because all surveillance and epidemiologic studies examining diet and physical activity in relation to health depend on the strength of assessment methods, this international conference was devoted to improving methods and measures of diet and physical activity. The conference was co-sponsored by the NIH Office of Dietary Supplements, the National Cancer Institute Applied Research Program, Active Living Research and the Robert Wood Johnson Foundation.
8th Annual Oxford International Conference on the Science of Botanicals
April 6–9, 2009
The purpose of this conference was to review, discuss, and explore the confluence of current research topics in natural product chemistry, pharmacognosy, and botanicals. Topic areas included authentication, cultivation, collection, and post-harvest practices for producing quality plant material, and chemical, toxicological methods for quality/safety assessment of botanicals. This conference was supported by a cooperative agreement between the National Center for Natural Products Research (NCNPR) and the Center for Food Safety and Applied Nutrition (CFSAN) of the U.S. Food and Drug Administration (FDA), along with Shanghai Institute of Materia Medica/CAS, China, The Council of Scientific & Industrial Research (CSIR, India), American Society of Pharmacognosy (ASP) and the Society for Medicinal Plant Research (GA).
Dietary Supplement Element Methodology Workshop
March 23–24, 2009
The purpose of this workshop was to evaluate the state of analytical methods for nutrient and non-nutrient minerals (including toxic elements) in dietary supplement products and to identify gaps in methodology, with a view toward designing a research program to fill the unmet methods needs of stakeholders.
Analytical Methods and Reference Materials Program Stakeholders' Meeting
September 10, 2007
The Office of Dietary Supplements (ODS) at the National Institutes of Health held a public meeting to solicit comments to assist the ODS with the continued implementation of an overall strategy for research, development, validation, and dissemination of analytical methods and standard reference materials for dietary supplement ingredients.
Vitamin D and Health in the 21st Century
September 5–6, 2007
This conference sought to evaluate available evidence on the efficacy and safety of vitamin D, identify gaps in knowledge on the efficacy and safety of vitamin D in general and across the life cycle, inform NIH and other Federal agencies on research priorities in the area of vitamin D and health, and disseminate the conference proceedings and executive summary to inform the broader nutrition community.
Black Cohosh Safety Workshop
June 28, 2007
This workshop was a follow-up to the November 22, 2004 Black Cohosh workshop convened by NCCAM and ODS. The purpose of this second workshop in 2007 was to update and improve our understanding of the safety issues surrounding this botanical. The workshop provided brief overviews of the pre-clinical and clinical research conducted and published over the 30 months since the last workshop. Academic and industrial scientists presented results of their studies on the species. Regulatory scientists from countries that had recently addressed the marketing of black cohosh were asked to explain their stances and presented the clinical data that were the basis of policy changes, if any.
The Science of Botanical Supplements for Human Health: A View from the NIH Botanical Research Center Program
April 28, 2007
At this workshop that took place at the 2007 Experimental Biology Meeting, scientists from all six Botanical Research Centers funded by ODS and the National Center for Complementary and Alternative Medicine (NCCAM), discussed a spectrum of research activities ranging from plant identification to clinical investigation. Investigators shared strategies used in standardizing botanicals as research materials, applying newer technologies to botanicals research, and assessing efficacy of botanical preparations in early phase clinical trials. The goal of the centers is to advance the scientific base of knowledge about botanicals, including issues of their safety, efficacy, and biological action.
What You Need to Know About Multivitamin and Mineral Supplements, FNCE 2006
September 17, 2006
The purpose of this session was twofold: 1) to provide information about the state of the science on associations between use of multivitamin/mineral supplements with chronic disease risk in adults; to review the findings of a systematic evidence-based review commissioned by NIH on this topic; and the implications for dietetic practice; and 2) provide findings from recent nationwide (National Health and Nutrition Examination Survey) population-based surveys of total dietary intakes of children and adolescents, including dietary supplement use; and to summarize implications for dietitians in the planning and assessment of dietary intakes.
5th Oxford International Conference on the Science of Botanicals
August 21–24, 2006
The purpose of this conference was to review, discuss, and explore methods for determining the identity, purity, quality, and processing of plants, commonly known as botanicals. Topic areas included authentication, cultivation, collection, and post-harvest practices for producing quality plant material, and chemical, toxicological methods for quality/safety assessment. This conference was supported by a cooperative agreement between the National Center for Natural Products Research (NCNPR) and the Center for Food Safety and Applied Nutrition (CFSAN) of the U.S. Food and Drug Administration (FDA) along with Council of Scientific & Industrial Research (CSIR, India).
47th Annual Meeting of the American Society of Pharmacognosy: Natural Products On Target
August 5–9, 2006
The following topics were presented at this meeting: 1) Synthetic and Biosynthetic Paths to Natural Products; 2) Clinical Evaluation of Herbs and Supplements: Trials, Toxicology and Drug Interactions; 3) Chemical Biology of Natural Products I: Molecular Targets; and Chemical Biology of Natural Products II: Molecular Methods.
North American Research Conference on Complementary & Integrative Medicine
May 24–27, 2006
This conference showcased original scientific research through keynote and plenary presentations, oral and poster presentations, and innovative interactive sessions. Presentations included research in basic science, clinical studies, methodology, health services, and education.
NIH State-of-the-Science Conference on Multivitamin/Mineral Supplements and Chronic Disease Prevention
May 15–17, 2006
It is estimated that more than one-third of American adults take multivitamin/mineral (MVM) supplements regularly. Recommendations regarding supplement use from expert groups vary widely, as does the strength of the evidence supporting such guidelines. The goal of this conference was to assess the evidence available on MVM use and outcomes for chronic disease prevention in adults, and to make recommendations for future research.
Zinc, Alcohol, and the Immune System
May 11, 2006
The purpose of the workshop was to review the scientific evidence reagarding the following: 1) Alcohol abuse and zinc depletion undermine the immune system thereby increasing susceptibility to infection. 2) Alcohol abuse and zinc depletion increase oxidative stress, and in this way cause tissue injury. 3) The mechanism of zinc action is through its possible restorative effects on the immune system and/or antioxidant pathways. 4) Zinc deficiency is a risk factor for alcohol-induced liver injury. 5) Consumption of zinc is a safe and effective means of affording protection from alcohol-induced tissue injury. Based on an assessment of the state-of-the-science, the panel identified gaps in the knowledge and made recommendations for targeted initiatives in basic and translational research.
Biological/Environmental Reference Materials Symposium
April 30 – May 4, 2006
The Tenth International Symposium on Biological and Environmental Reference Materials, BERM 10, was held in Charleston, South Carolina. As a continuation of the symposium series held alternately in the European Union and the United States since 1983, BERM 10 was a forum to address issues related to the development of biological and environmental reference materials and their role in the quality assurance of analytical measurements.
Why, When, What, and How of Clinical Trials: Educational Sessions
November 9, 2005
With growing recognition of the importance of conducting clinical trials to evaluate the safety and efficacy of dietary supplements, the Office of Dietary Supplements (ODS) was invited to organize three educational sessions at the November 2005 SupplySide West International Trade Show and Conference. The sessions featured scientists from academia and the government who spoke on the value of conducting clinical trials, designing trials to test hypotheses, appropriate selection of test materials and study subjects, and interpreting study findings, and funding clinical trials.
Dietary Supplement Use in the USA: Who's Using What and Why
October 24, 2005
Dietary supplement use is so pervasive in the United States today that it is becoming impossible to obtain estimates of total nutrient intakes without accounting for them. This session at the 2005 American Dietetic Association's Food & Nutrition Conference & Expo presented current data about why people use dietary supplements, how to collect and assess information about them, and some authoritative resources that dietitians can use.
Workshop on Diet, Nutrition, and Dietary Supplement Use in Autism: Evaluation of the Evidence
October 6, 2005
The workshop provided NIH with an overview of the current state of the science on dietary supplements and related interventions in managing autism; identified specific scientific questions concerning research needs and opportunities; and provided examples of the role of dietary supplements under investigation in management of autism spectrum disoder.
Role of Betaine in the Treatment of Alcoholic Liver Disease
October 3, 2005
This 1-day symposium explored the role of betaine in the treatment of alcoholic liver disease. The meeting was sponsored by the National Institute on Alcohol Abuse and Alcoholism, the Office of Dietary Supplements, and the National Center for Complementary and Alternative Medicine.
Omega-3 Fatty Acids and their Role in Cardiac Arrhythmogenesis Workshop
August 29–30, 2005
The major goals for this workshop were to: (1) review the epidemiological evidence and the data from randomized trials on the role of omega-3 fatty acids in susceptibility to arrhythmias and sudden cardiac death; (2) explore the basic mechanisms by which omega-3 fatty acids affect cardiac excitability at the cellular and organ level; (3) identify the gaps and barriers in basic understanding of the effects of omega-3 fatty acids on cardiac electrical activity at the cellular, tissue, and whole body levels; and (4) provide prioritized recommendations for additional research studies to (a) better understand the basic mechanisms coupling omega-3 fatty acids to cardiac electrical activity and (b) facilitate translation of this knowledge to the treatment and prevention of cardiac arrhythmias.
Use and Misuse of Biomarkers as Indicators of Cancer Risk Reduction Following Dietary Manipulation
July 12–13, 2005
The purpose of this workshop was to provide the scientific community and lay public a general background regarding biomarker validation. The conference goals were to review and discuss the criteria for surrogate endpoints for cancer risk, identify biomarkers that are influenced by diet and determine their relationship to cancer risk and tumor behavior, and explore emerging biomarkers for their relevance to nutrition and cancer prevention.
Bioactive Food Components Meetings
March 24 – April 1, 2005
In these meetings, the Office of Dietary Supplements and other interested parties in the Federal government explored existing and new approaches in evaluating the significance of bioactive food components in health promotion and disease prevention.
An NIH Conference on Dietary Supplements, Coagulation, and Antithrombotic Therapies
January 13–14, 2005
This national conference was convened to increase the understanding of the potential for dietary supplements to interfere with hemostasis and antithrombotic therapies. Cosponsors included the National Heart, Lung, and Blood Institute and ODS.
Carnitine: the science behind a conditionally essential nutrient
March 25–26, 2004
This 2-day conference addressed topics related to carnitine. The meeting was sponsored by the National Institute of Child Health and Human Development, the National Center for Complementary and Alternative Medicine, the National Institute of Mental Health, and the Office of Dietary Supplements.
Role of Iron in Alcoholic Liver Disease
October 25, 2002
Antioxidants with Concurrent Cancer Therapies: To Use or Not to Use?
October 21, 2002
Held at the American Dietetic Association's Food & Nutrition Conference & Exhibition 2002
Nutritional Genomics and Proteomics in Cancer Prevention
September 5–6, 2002
Mechanistic Studies of Cardiovascular Effects of Botanicals
August 22–23, 2002
Future Directions for the CSFII/NHANES Diet Nutrition Survey: What We Eat in America
June 20–21, 2002
The 11th International Symposium on Trace Elements in Man and Animals (TEMA11)
June 2–6, 2002
Perspectives on Conjugated Linoleic Acid Research, Current Status and Future Directions
May 15–16, 2002
Botanical Dietary Supplements: Health Effects and Mechanisms of Action
April 22, 2002
Held at Experimental Biology 2002
Dietary Supplements Analytical Methods Workshop
April 18, 2002
ODS Dietary Supplements Methods and Reference Materials Program
February 8, 2002
Dietary Supplement Use in Women: Current Status and Future Directions
January 28–29, 2002
A Conference on the Science and Policy of Performance-Enhancing Products
January 8–9, 2002
Interventions for Metabolic and Endocrine Complications of HIV/AIDS and Drug Abuse
November 26–27, 2001
Do Herbal Products Affect Quality of Life Issues for Women?
October 22, 2001
Held at the American Dietetic Association's Food & Nutrition Conference & Exhibition 2001
Role of S-Adenosyl-L-Methionine (SAMe) in the Treatment of Alcoholic Liver Disease
September 7, 2001
Diet, DNA Methylation Processes and Health
August 6–8, 2001
Assessment of Dietary Supplement Use, Workshop on Database Needs
July 25, 2001
Cellular and Molecular Aspects of Omega-3 Fatty Acids and Cancer
June 28–30, 2001
Exploring Opportunities for Collaboration with Industry
May 14, 2001
Videoconference from Iowa State University: Current Issues in Nutrition, Our Changing Food Supply
April 26, 2001
Botanical Dietary Supplements
April 1, 2001
Experimental Biology 2001
Shape Up America!'s DiabesityTM Conference
March 24–25, 2001
Essential Fatty Acids in Health Maintenance and Disease Prevention
March 20, 2001
Diets, Antioxidants and Environmental Influences on Health and Disease
March 13–14, 2001
Nutritional Therapy in Medical Practice
February 24–26, 2001
Sponsored by the Beth Israel Medical Center Continuum Center for Health and Healing
Dietary Supplement Use in Children
February 12–13, 2001
Omega-3 Fatty Acids, Diabetes and Cardiovascular Risk. An International Workshop
November 30 – December 2, 2000
Nutrition and Oral Infectious Disease
November 5–7, 2000
Vitamin E in the Prevention of Diabetes Complications
October 23, 2000
Is There a Role for Dietary Supplements in the Management of Diabetes? Lessons from Clinical Studies
October 16, 2000
American Dietetic Association's Food & Nutrition Conference & Exhibition
Medicine for the Public lecture series sponsored by the Clinical Center at the National Institutes of Health: Dangerous Liaisons - Drugs and Herbal Products
October 3, 2000
(Real Player required)
ODS-sponsored Science Panel from the Consumer Healthcare Products Association Annual Dietary Supplements Symposium
September 28–29, 2000
The Importance of Omega-3 Fatty Acids in the Attenuation of Immune-Mediated Diseases
September 18, 2000
Eighth International Symposium on Biological and Environmental Reference Materials (BERM-8), including "Workshop on Botanical and Dietary Supplement Standard Materials"
September 17–22, 2000
Exporting the Science of Nutraceuticals
American Association of Pharmaceutical Scientists Dietary Supplements Forum
June 28–30, 2000
Metals in Medicine - Targets, Diagnostics, & Therapeutics
June 28–29, 2000
National Nutrition Summit
May 30–31, 2000
Essential Fats in Foods
March 20, 2000
The Efficacy and Safety of Medicinal Herbs
March 2–3, 2000
Conference Proceedings: The Efficacy and Safety of Medicinal Herbs International Conference. Public Health Nutrition 2000; 3(4A).
Copies of the Conference Proceedings may also be ordered from UNC Institute of Nutrition, PO Box 2435, Chapel Hill, NC 27515.
Indo-U.S. Workshop on Health and Nutrition of Women, Infants and Children
February 10–12, 2000
Bioavailability of Nutrients and Other Bioactive Components of Dietary Supplements: Defining the Research Agenda
January 5–6, 2000
Chromium and Diabetes
November 4, 1999
Prevention of Craniofacial Anomalies
September 22–23, 1999
Micronutrients and Infectious Diseases: Cellular and Molecular Immunomodulatory Mechanisms
September 16–17, 1999
Antioxidants: Strategies For Interventions In Aging and Age-Related Diseases
July 14–16, 1999
- Workshop Summary
Antioxidant Strategies for Interventions in Aging and Age-Related Diseases. Antiox Redox Signal. 2000, Fall;2(3):375-471.
Phytoestrogens and Healthy Aging
June 3–4, 1999
Nutrient Metabolism in the Genetic Anemias and Dietary Supplements of Potential Benefit to Patients with Sickle Cell Disease
May 24–25, 1999
International Collaborative Research Project on Fluorides: Research Needs
May 10–12, 1999
Dietary Supplements of Potential Benefit to Patients with Sickle Cell Disease
May 6–8, 1999
Nutritional Implications of Cephalic Phase Responses
April 14, 1999
The Essentiality of Omega-6 and Omega-3 Fatty Acids
April 7–9, 1999
Zinc and Health
November 4–6, 1998
Zinc and Health: Current Status and Future Directions (Workshop: Novmeber 4-5, 1998)
Zinc: What Role Might Supplements Play (Conference: November 6, 1998)
International Workshop to Evaluate Research Needs on the Use and Safety of Medicinal Herbs
September 23–24, 1998
Coenzyme Q10 and the Aging Process
August 31 – September 1, 1998
Metabolic, Endocrine and Gastrointestinal Disorders in Drug Abuse and HIV/AIDS
August 3–4, 1998
Workshop Proceedings: Metabolic, Endocrine, and Gastrointestinal (MEG) Disorders in Drug Abuse and HIV/AIDS. Journal of Acquired Immune Deficiency Syndromes 2000; 25(Suppl 1).
Nutritional Supplements, Botanical Products and Functional Foods
April 18, 1998
Experimental Biology 1998
Frontiers in Antioxidant Research, American Society for Parenteral and Enteral Nutrition
January 19, 1998
22nd Annual Clinical Congress