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Role of Iron in Alcoholic Liver Disease

Role of Iron in Alcoholic Liver Disease

Sponsored by: National Institute on Alcohol Abuse and Alcoholism
and the
Office of Dietary Supplements

Friday, October 25, 2002
Hyatt Regency, Bethesda, MD


    Vishnudutt Purohit, Ph.D.
    Program Director
    Biomedical Research Branch/Division of Basic Research
    National Institute on Alcohol Abuse and Alcoholism
    National Institutes of Health
    6000 Executive Boulevard/ suite 402
    Bethesda, M.D., 20892-7003
    Phone: (301) 443-2689; Fax: (301) 594-0673


7:45 - 8:30 Breakfast
8:30 - 8:40 Opening Remarks
Sam Zakhari, Ph.D., NIAAA/NIH
Paul Coates, Ph.D., ODS/NIH
8:40 - 9:00 Introduction to the Symposium
Vishnudutt Purohit, Ph.D., NIAAA/NIH
Christine Swanson, Ph.D., ODS/NIH
Morning Session: Chairperson: Bin Gao, M.D., Ph.D., NIAAA/NIH
9:00 - 9:40 An Overview of Iron Metabolism
Tracy Rouault, M.D., NICHD/NIH
9:40 - 10:20 Iron-Dependent Macrophage Cell Activation in Alcoholic Liver Disease
Hidekazu Tsukamoto, D.V.M., Ph.D., University of Southern California
10:20 - 10:50 Break
10:50 - 11:30 Iron and CYP2E1-Induced Oxidative Stress in Alcoholic Liver Disease
Arthur I. Cederbaum, Ph.D., Mount Sinai School of Medicine, New York
11:30 - 12:10 Iron-Induced Oxidant Stress and Liver Fibrogenesis
Antonello Pietrangelo, M.D., Ph.D., University of Modena and Reggio Emilia, Italy
12:10 - 1:15 Lunch
Afternoon Session: Chairperson: Denise Russo, Ph.D., NIAAA/NIH
1:15 - 1:55 Hemochromatosis and Alcoholic Liver Disease
Lawrie W. Powell, M.D., Ph.D., The Queensland Institute of Medical Research, Australia
1:55 - 2:35 Iron in non-Hemochromatic Liver Diseases
Herbert Bonkovsky, M.D., University of Connecticut Health Center, Connecticut
2:35 - 3:00 Break
3:00 - 3:40 Iron and Cancer
Yves Deugnier, M.D., Service des Maladies du Foie CHU Pontchaillou, France
3:40 - 4:20 Iron Chelators and Iron Toxicity
Gary M. Brittenham, M.D., Columbia University, New York
4:20 - 5:20 Discussion
David Brenner, M.D., University of North Carolina at Chapel Hill
Patricia Greenwel, Ph.D., CSR/NIH