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| 8:30 A.M. |
Welcome
Carlos A. Gonzalez, Ph.D. — Chief, Chemical Sciences Division, NIST
Paul Coates, Ph.D. — Director, Office of Dietary Supplements (ODS), National Institutes of Health (NIH)
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| Session 1 |
Vitamin D Laboratory Measurement: Defining the Problem
Moderator: Christopher Sempos, Ph.D. — ODS, NIH
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| 8:45 A.M. |
VDSP Overview and Meeting Agenda
Christopher Sempos, Ph.D. — ODS, NIH
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| 9:00 A.M. |
Lack of Standardization: Clinical Impact
Neil Binkley, M.D. — University of Wisconsin-Madison
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| Session 2 |
The VDSP Reference Measurement System: Initial Results on Interlaboratory Comparison
Moderator: Katleen Van Uytfanghe, Ph.D. — Ghent University
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| 9:15 A.M. |
VDSP Reference Measurement System: NIST Components, Current and Future
Stephen Wise, Ph.D. — NIST
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| 9:30 A.M. |
Discussants: Donald Walt Chandler, Ph.D. — Laboratory Corporation of America (LabCorp) and Nigel J. Clarke, Ph.D. — Quest Diagnostics
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| 9:45 A.M. |
Value Assignment and Uncertainty Evaluation for the Samples Used in the VDSP Interlaboratory and Commutability Studies
Antonio Possolo, Ph.D. — NIST
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| 10:00 A.M. |
Break
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| 10:15 A.M. |
VDSP Reference Measurement System: Vitamin D Standardization Certification Program (VDSCP) and Interlaboratory Comparison Study Results
Hubert Vesper, Ph.D. — Centers for Disease Control and Prevention (CDC)
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| 10:40 A.M. |
Discussants: James Freeman, Siemens Healthcare and Andre Valcour, Ph.D. — LabCorp
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| 11:00 A.M. |
Open Discussion
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| Session 3 |
The VDSP Reference Measurement System: External Quality Assessment/Proficiency Testing (EQA/PT) Programs and Commutability
Moderator: Gary Myers, Ph.D. — American Association for Clinical Chemistry (AACC)
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| 11:15 A.M. |
Why Commutability Matters
Gary Myers, Ph.D. — AACC
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| 11:30 A.M. |
VDSP Commutability Study Results
Karen W. Phinney, Ph.D. — NIST
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| 11:45 A.M. |
VDSP Reference Measurement System: The Role of Accuracy-Based EQA/PT Schemes
Graham Carter — Imperial College Healthcare, Charing Cross Hospital, Vitamin D External Quality Assessment Scheme (DEQAS)
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| 12:00 NOON |
NIST Value Assignment of DEQAS Samples
Johanna Camara, Ph.D. — NIST
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| 12:10 P.M. |
College of American Pathologists (CAP) Accuracy-Based Vitamin D (ABVD) Survey
Andrew Hoofnagle, M.D., Ph.D. — University of Washington and CAP
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| 12:20 P.M. |
NIST-NIH Vitamin D Metabolites Quality Assurance Program (VitDQAP)
Mary Bedner, Ph.D. — NIST
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| 12:30 P.M. |
Discussants: Ronald L. Horst, Ph.D. — Heartland Assays, LLC and Joshua Soldo — DiaSorin, Inc.
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| 12:45 P.M. |
Open Discussion
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| 1:00 P.M. |
Lunch Break
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| Session 4 |
Impact of Standardization and VDSP Assessment
Moderator: Robyn Lucas, M.B.Ch.B., Ph.D. — The Australian National University
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| 2:15 P.M. |
Standardizing Past 25(OH)D National Survey Data: The Irish Experience and Implications for Re-assessing Vitamin D Requirements in Europe
Kevin Cashman, Ph.D. — University College Cork
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| 2:30 P.M. |
Standardizing Past 25(OH)D National Survey Data: The Impact of Standardization on the Interpretation of Data from the Canadian Health Measures Survey
Stephen Brooks, Ph.D. — Health Canada
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| 2:45 P.M. |
Discussant: Public Health Impact of Standardization
Robyn Lucas, M.B.Ch.B., Ph.D. — The Australian National University
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| 3:00 P.M. |
Discussants: Standardizing Old Research Data: Importance to Clinical Research
Daniel D. Bikle, M.D., Ph.D. — University of California San Francisco and Neil Binkley, M.D. — University of Wisconsin-Madison
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| 3:15 P.M. |
Open Discussion
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| 3:30 P.M. |
Break
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| Session 5 |
VDSP So Far and Plans for the Future
Moderator: Ian Young, M.D., Ph.D. — Royal Victoria Hospital, Belfast, International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)
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| 4:00 P.M. |
VDSP So Far and Plans for the Future
Christopher Sempos, Ph.D. — ODS, NIH
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| 4:15 P.M. |
Open Discussion with VDSP Panelists
- Christopher Sempos, Ph.D. — ODS, NIH
- Stephen Wise, Ph.D. — NIST
- Katleen Van Uytfanghe, Ph.D. — Ghent University
- Hubert Vesper, Ph.D. — CDC
- Graham Carter — Imperial College Healthcare, Charring Cross Hospital, DEQAS
- Andrew Hoofnagle, M.D., Ph.D. — University of Washington and CAP
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| 4:45 P.M. |
Discussant: Ian Young, M.D., Ph.D. — Royal Victoria Hospital, Belfast, IFCC
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| 5:00 P.M. |
Closing Comments
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| 5:15 P.M. |
Adjourn
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