Folate - Change History

Fact Sheet for Consumers

November 30, 2022

View change — Revised text to state that people with a genetic polymorphism, 677C>T, in the methylenetetrahydrofolate reductase (MTHFR) gene have a reduced ability to convert folate to one of its active forms, 5-MTHF.

November 1, 2022

Updated the summary to address the latest CDC guidance on folic acid for people with an MTHFR polymorphism who could become pregnant.

March 29, 2021

Updated the Daily Value text, linked to the new edition of the Dietary Guidelines for Americans, and updated the associated text.

June 3, 2020

Updated the link to the Dietary Supplement Label Database in reference 21.

March 11, 2020

Updated Sources of Folate to reflect the new Daily Value and the new Nutrition Facts and Supplement Facts Labels.

July 19, 2019

Editorial changes were made in the Health Risks from Excessive Folate section.

July 9, 2019

Updated the link to USDA’s FoodData Central.

October 4, 2018

This fact sheet was comprehensively reviewed and extensively revised.

March 2, 2018

Updated Dietary Reference Intake definitions.