Omega-3 Fatty Acids - Change History

Fact Sheet for Health Professionals

December 17, 2024

View change — Corrected the wording for how fish acquire omega-3s from microalgae.

February 15, 2023

Revised the Dietary Supplements section to include additional research on the bioavailability of krill oil.

July 18, 2022

Updated the Cardiovascular disease (CVD) and CVD risk factors section, Dry eye disease section, and Safety of Omega-3s section to add the STRENGTH clinical trial and the recent ancillary study from the VITAL trial on dry eye disease.

June 2, 2022

Revised wording to reflect current scientific consensus that obesity is a disease.

August 4, 2021

Revised text to state that the FDA has concluded that dietary supplements providing no more than 5 g/day EPA and DHA are safe when used as recommended; also updated reference 178.

March 26, 2021

Linked to and cited the new edition of the Dietary Guidelines for Americans and updated the associated text.

October 1, 2020

The cardiovascular disease (CVD) and CVD risk factors section was extensively revised and updated.

January 6, 2020

Corrected the link for reference for 17 and 67.

July 9, 2019

Updated the link to USDA’s FoodData Central.

June 11, 2019

Corrected reference 136, Zhang et al.

November 21, 2018

Added results of the newly published VITAmin D and OmegaA-3 TriaL (VITAL) on cardiovascular disease and cancer.

June 6, 2018

Added a new section on dry eye disease and updated the section on cardiovascular disease.

March 2, 2018

Updated Dietary Reference Intake definitions.